ABSTRACT

Introduction: Primary dosage forms are basic preparations whose shelf life is a challenge for the practice. Kwatha is a basic primary preparation which is easily prone to contamination and can be marketed only by the addition of suitable preservatives to increase the shelf life. So addition of preservatives is being practiced to prolong the shelf life of kwatha but use of chemical preservatives are harmful to body and even have carcinogenic effects. Hence there aroused a need to find natural preservatives to benefit the mankind. Arka which is a water distillate consists of essential substances from the crude drug and has longer shelf life comparatively. Nagakesara arka possess anti- microbial and anti- oxidant properties and economically cheaper and easily available drug and triphala kwatha being useful in many purposes, in this study an attempt was made to elucidate the preservative action of nagakesara arka in triphala kwatha. Materials and methods: Includes preparation of nagakesara arka, triphala kwatha and conduction of analytical and microbiological study to see the preservative action using SDA and MHA media. Observationsand Results: Study follows observations over microbial growth of the sample on daily basis where nagakesara arka showed preservative action for 25 days. Aspergillus niger was the fungal growth seen on 26th day. Discussion: Nagakesara arka owing to its pH, chemical constituents and other properties preserved the triphala kwatha for a stipulated period of time. Conclusion: From the study, it was concluded that the nagakesara arka preserved triphala kwatha without any microbial contamination for 25 days which was added in the concentration of 15% Keywords: Nagakesara arka, Triphala kwatha, Preservative, Microbiological study
Publication date: 01/07/2024

https://ijbpas.com/pdf/2024/July/MS_IJBPAS_2024_8176.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.7.8176