ABSTRACT

Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder noted in the general population worldwide. Its chronic nature, signs and symptoms which vary periodically from mild to severe have many negative effects on the quality of life for the sufferer; therefore the appropriate treatment of these patients is highly important. Patients should be informed by their doctors that the nature of the disease is benign, and educated on how to deal with and control symptoms of the disease. Herbal drugs are also one of the major classes of over the counter drugs used by patient considering its safety. Hence, in present study we attempted to prepare two formulations, one is aluminium hydroxide suspension and second is combination of calcium carbonate and magnesium oxide suspension as well as compares this by marketed formulation through IBS activity using in vitro methods viz- acid-Neutralizing capacity and buffering capacity. From the results of present study, it may be concluded that our both formulations show good physicochemical properties for the treatment of IBS. Keywords: Intestinal bowel syndrome (IBS), Herbal drug, Formulation, Suspension
Publication date: 01/07/2024

https://ijbpas.com/pdf/2024/July/MS_IJBPAS_2024_8175.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.7.8175