ABSTRACT

Oral squamous cell carcinoma (OSCC) is among the most common cancers worldwide. Late diagnosis precludes to poor prognosis. A major barrier in early detection of cancer is the lack of early detection protocols. This has warranted the need for novel methods of cancer detection. The non-invasiveness and ease of handling saliva as a diagnostic tool can be considered as a useful adjuvant in oral cancer detection. The analysis of salivary biomarkers (proteomics, genomics, & metabolomics) will be a promising tool in early detection and management of OSCC. This literature review aims to categorize the various salivary biomarkers that have been identified in oral squamous cell carcinoma. A PubMed literature search was conducted and relevant articles were reviewed. Keywords: Oral squamous carcinoma; saliva; salivary biomarkers; cancer detection
Publication date: 01/07/2024

https://ijbpas.com/pdf/2024/July/MS_IJBPAS_2024_8143.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.7.8143