ABSTRACT

Reviewing, the issue of antimicrobial resistance, which is one of the most urgent topic of public health today, chemists are working towards the development of medicinal agents of therapeutic importance. The development of resistance such as multi-drug resistance towards various antibiotics or adopted by bacterial strains possesses a challenge to the scientific community for the innovation of new remedies. Thus, there is an ample need to develop newer and more effective drug molecules with high safety profiles. The main objective is to find synthetic chemical compounds that can be fused with a number of heterocyclic to generate medicinal compounds of therapeutic importance. One of such compound is Benzothiazole consisting of a benzene ring fused with the d face (4, 5 position) of thiazole. The benzothiazole moiety possesses various biological activities thus representing as an active biological compound with diverse properties. This review focuses on already available benzothiazole nucleus containing drugs and their action and also about the various modifications that can be done on this moiety. Keywords: Benzothiazole, Pharmacology, Anti-cancer, Anti diabetic, Anti tubercular
Publication date: 01/06/2024

https://ijbpas.com/pdf/2024/June/MS_IJBPAS_2024_8123.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.6.8123