ABSTRACT

Transmitting drug through nose to the brain is difficult. In reality there are many neurological illnesses that call for the treatments where the medicine must cross a blood brain barrier and go through the brain, Alzheimer's disease, Multiple sclerosis and other illnesses of central nervous system are becoming more and more public health concern partly due to longer life expectancies and an ageing population. Although treatments have access to the brain via these channels, the primary drawbacks of this strategy is only a few drug absorption and nasal permeability. This article will describe the routes by which drugs go from the nose to the brain and the toxicity of nanoparticles, the necessity of nanostructured lipid carriers (NLCs) in combination with an drug delivery intranasally to specifically target the brain. Keywords: Nose to Brain Drug Delivery, Olfactory, Nanocarriers, Transport Pathways, Brain Targeting
Publication date: 01/06/2024

https://ijbpas.com/pdf/2024/June/MS_IJBPAS_2024_8122.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2024/13.6.8122