ABSTRACT

Nanotechnology is being widely used in various fields such as medicine, cosmetics, and lifestyle. Some daily-use products in which we can find nanomaterials include pharmaceuticals, fabrics, rubber-based products, plastics, and cosmetics. Hence it is evident that the usage of nanomaterials is increasing day by day. Therefore, this is causing an increase in exposure to nanomaterials. The effect of this exposure is being explored through numerous studies over the decades. The studies have revealed some effects such as DNA damage, oxidative stress, lipid peroxidation, and mitochondrial damage. Based on the data gathered and further interpretation several laws and regulations have been laid to protect the interest of all the involved parties, be it the consumer, the manufacturer, or the nature. Formulation of these laws requires a lot of criteria to be considered, hence specialized regulatory bodies have been established to promote nanotechnology as well as create the rules and regulations. With the emergence of bioinformatics, the ill effects of nanomaterials can now be predicted in-silico providing an alternative to in vivo studies. This paper will explore all such recent developments and discoveries in the field of nanotoxicology. Keywords: nanomaterial, nanotechnology, DNA damage, oxidative stress, nanotoxicology, and engineered nanoparticles
Publication date: 01/06/2024

https://ijbpas.com/pdf/2024/June/MS_IJBPAS_2024_8083.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.6.8083