A REVIEW ON: MICROEMULGEL FOR TOPICAL DRUG DELIVERY SYSTEM Authors: Avinash Patel T V And Sheeba F R*
ABSTRACT
A topical drug delivery system is a localized method of administering drugs to specific areas
of the body through routes such as ophthalmic, skin, vaginal, and rectal. It is primarily used to
provide a local effect at the site of action and bypasses first-pass metabolism. Microemulgel is
a combination dosage form that combines the properties of a microemulsion and a gel. It
exhibits desirable characteristics like spreadability, thixotropy, transparency, biocompatibility,
emollient properties, and an elegant experience. With its dual release control system,
incorporating both hydrophilic and hydrophobic drugs is possible. Microemulgels are prepared
by incorporating a microemulsion into a gel matrix and evaluated for various parameters such
as spreadability, pH, rheological properties, swelling index, and in-vitro release studies. Due
to its micron-sized particles, microemulgels have excellent penetration through the stratum
corneum. In summary, microemulgels represent a promising approach for topical drug delivery
and hold potential for future applications in dermal care due to their dual release control system
and enhanced therapeutic activity compared to microemulsions.
Keywords: Microemulgel, Microemulsion, Gel, Novel topical drug delivery Publication date: 01/06/2024 https://ijbpas.com/pdf/2024/June/MS_IJBPAS_2024_8080.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.6.8080
