ABSTRACT

For delivering the drug in selective and effective amount to brain is very difficult due to various obstacles like BBB. BBB is most important hurdle which blocks uptake of various drug through systemic circulation to brain. The most convenient route to bypass BBB is intranasal route, as it allows only the required therapeutic amount to reach brain. These review covers capacity of nano emulsion given by nasal route to deliver the drug to brain, the pathways and mechanism of direct delivery from nose to brain, countless factors affecting nasal drug absorption, traditional as well as cutting-edge nasal delivery, and different methods for intranasal drug delivery and used devices. These send medication from nose-brain helps to treat various diseases in the brain. Keywords: Brain, medication targeting, nasal drug delivery, delivery systems, and delivery equipment
Publication date: 01/05/2024

https://ijbpas.com/pdf/2024/May/MS_IJBPAS_2024_8017.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2024/13.5.8017