ABSTRACT

Novel Drug Delivery System Novel drug delivery systems have gained high beneficial interests in the field of pharmaceutical sciences due to its enhanced therapy by enlarging the efficacy and duration of drug activity, improved patient compliance through reduced dosing frequency and convenient routes of administration and enhanced targeting for a specific site to decrease unwanted adverse effects. The provocation for both drug and drug delivery companies is to deliver both existing and emerging drug technologies in a way that enhances the welfare to the patients. Over the past several years, great progress has been made on evolution of novel drug delivery systems. The variety of novel formulations like polymeric nanoparticles, liposomes, microemulsions, microsphere has been reported using bioactive and plant extracts. The novel formulations are reported to have remarkable advantages over conventional formulations which include enhancement of solubility, bioavailability, protection from toxicity, improvement of pharmacological activity, improvement of stability, enhanced tissue macrophages distribution, sustained delivery, and protection from physical and chemical degradation. The present review highlights the current status of the development of novel formulations and summarizes their method of preparation, type of active ingredients, size, and entrapment efficiency, route of administration, biological activity and applications of novel formulations. Keywords: Novel Drug Delivery System, Nanoparticles, Microspheres, Liposomes
Publication date: 01/04/2024

https://ijbpas.com/pdf/2024/April/MS_IJBPAS_2024_7960.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.4.7960