ECO-FRIENDLY PREPARATION OF DIFFERENT QUINOXALINE ANALOGUES AND THEIR ANTI-DIABETIC EVALUATION Authors: Nagaraju G , DINESH B, PHANINDRA K, SAI KP, PUNDARIKAKSHAYYA P, RAMA RAO N
ABSTRACT
In an effort to develop newer quinoxaline derivatives synthesized by green synthetic techniques
and perform in vitro and in vivo evaluation for potent anti-microbial and anti-diabetic activities
respectively. To synthesize few newer quinoxaline derivatives and the synthesized quinoxaline
derivatives having antibacterial and anti-diabetic properties. When compared to all the
synthesized derivatives, QX2, and QX3 have a greater anti-microbial and anti-diabetic
activities, further characterization of derivatives was done by determining their melting point,
Retention factor from thin layer chromatography and spectroscopic studies. This research
article highlights the outcomes of quinoxaline derivatives by performing anti-diabetic activity.
This has shown a positive potency for some derivatives by assessing the microbial and
pharmacological activities by comparing them with standard marketed drugs.
Keywords: Quinoxaline, Anti-diabetic, Anti-microbial, Alloxan, Green Synthesis Publication date: 01/04/2024 https://ijbpas.com/pdf/2024/April/MS_IJBPAS_2024_7957.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.4.7957