EVALUATION OF ANTIINFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF MANILKARA ZAPOTA SEEDS IN RODENTS
Authors: Padmavathi B , BADRINATH J, PHANINDRA KUMAR A, KONDA NAIK B, NARENDRA P, NATARAJA RAO K, TEJESHWAR R, RAVINDRA Y, DAVID RAJU P AND RAMARAO N

ABSTRACT
Manilkara zapota a naturally occuring seasonal plant belonging to the family sapotaceae. The fruits and seeds of this plant are very nutritious and they also have several medicinal properties. It is widely used as the immunity booster and prevent inflammation. It belongs to the nativity of the southern Mexico and also across Central America. The present study explains the anti inflammatory activity of ethanolic extract of the seeds of Manilkara zapota . The extract prepared was administered orally for 2 hours with 30 min interval in two doses (100 mg/kg and 200 mg/ kg). As the dose increases the extract successfully decreased the inflammation caused by the egg albumin (1 ml/kg). Anti inflammatory activity was examined by using the digital plethysmometer. The anti inflammatory activity is mainly due to presence of flavonoids These findings justify that traditional use of Manilkara zapota seeds can be beneficial to mankind. Keywords: Manilkara zapota L, Sapotaceae, Anti-inflammatory, Flavonoid
Publication date: 01/04/2024
    https://ijbpas.com/pdf/2024/April/MS_IJBPAS_2024_7949.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.4.7949