ABSTRACT

Medicinal plants used for the antimicrobial treatment started in ancient times. Even in all over the world modern medicine is available, the interest on plant medicines and their utilization have been increasing rapidly in recent years. Several medicinal plant extracts and its phytochemicals have shown activity against all types of microorganisms including both Gram-negative and Gram-positive bacteria. Herbal medicines have recently attracted the great interest towards their versatile application, the present work is to formulate and evaluate the ointment of C.longa rhizome and C.roseus flower extract. The extracts were prepared by using maceration method. The ointment base was prepared and formulation of ointment was done by incorporating the extract in the base by levigation method. After completion of formulation it was evaluated for its physicochemical parameters and for its stability. Thus it could become a media to use the medicinal properties of C.longa rhizome and C.roseus flower effectively and easily as a simple dosage form. The antimicrobial activity of optimized formulation was showed significant activity against the tested bacterial pathogens. The present study confirmed the antimicrobial activity of the formulations. The results are the justification for the use of the herbal medicine. Keywords; Curcuma longa, Cathranthus roseus, Maceration, Levigation, Spredability
Publication date: 01/04/2024

https://ijbpas.com/pdf/2024/April/MS_IJBPAS_2024_7935.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.4.7935