SCREENING OF TRADITIONALLY USED MEDICINAL PLANTS IN INDIA FOR POTENTIAL ANTIBACTERIAL, ANTIFUNGAL AND ANTIOXIDANT ACTIVITY
Authors: Ahmad F , ANJUM N, WASEEM S AND MISHRA RS

ABSTRACT
The goal of the current study is to test a variety of herbs used in Indian folk medicine for their potential antibacterial, antifungal, and antioxidative properties. The study's objective was to identify an active plant extract that would be helpful in the development of new lead chemicals to treat fatal diseases [1]. Nine herbs, including Emblica officinalis, Withania somnifera, Aegle marmelos, Bacopa monnieri, Tinospora cordifolia, Plantago ovate, Garcinia indica, Glycyrrhiza glabra, and Ocimum sanctum, were chosen for preliminary screening for their antibacterial, antifungal, and anti-oxidant potentiality. Methanol extracts were more powerful than aqueous extracts, according to the results of the initial screening experiment. Gram-positive bacteria were more susceptible to the effects of the plant extracts than gram-negative bacteria. The bacterias K. pneumoniae and E. coli were the most sensitive and resistant, respectively. The antibacterial activity of Bauhinia variegata L. was astounding. In the modern world, fungi infections are a substantial cause of illness and mortality, particularly in people with impaired immune systems [14]. Aqueous and dichloromethane extracts of nine plants historically used to treat fungus infections. Results confirm the likelihood that commonly used plants could serve as a source of novel medications for the treatment of fungus diseases. In addition, the 2,2-diphenyl-1-picrylhydrazyl radical and linoleic acid peroxidation were tested against the antioxidant activity [29] and radical scavenging activity of methanolic extracts of specific plant materials historically utilized by Indians as folk treatments. Keywords: antibacterial, antifungal, antioxidative, Methanol extracts, gram-positive bacteria, gram-negative bacteria, immune systems, linoleic acid peroxidation and folk treatments
Publication date: 01/04/2024
    https://ijbpas.com/pdf/2024/April/MS_IJBPAS_2024_7793.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.4.7793