ABSTRACT

Today diabetes become a global concern and recent report revel that 422 million people suffer form the diabetes. 90 – 95 % case are type 2 diabetes. An update on spectrophotometric and chromatographic techniques for determining teneligliptin and dapagliflozin is the major goal of this review. The concentrations of Teneligliptin and Dapagliflozin are measured using UV, HPLC, HPTLC, UPLC, and LC/MS methods. Extensive studies describing various analytical methods have been conducted on dapagliflozin and teneligliptin. Spectrophotometric (UV) methods for Teneligliptin and Dapagliflozin alone and in combination with other drugs include parameters like a solvent, ?max, Range, Regression Coefficient etc. chromatographic methods (HPLC, HPTLC, and UPLC) for Teneligliptin and Dapagliflozin alone and combination with other drug include parameter like stationary phase, mobile phase, flow rate, ?max, Range, Regression Coefficient, retention time and Rf value etc. Additionally, this review gives comprehensive details on the circumstances for the separation of Teneligliptin and Dapagliflozin both alone and in combination with other medications, as well as the existence of its degradation products. Keywords: Teneligliptin, Dapagliflozin, HPLC, HPTLC, LC-MS, UPLC, UV
Publication date: 01/03/2024

https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_7880.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.3.7880