ABSTRACT

Dapsone is used for treating wide range of disease condition like dermatitis, herpetiformis, Hansen’s disease etc. Dapsone is fall under class of drug known as sulfones. It works by slowing down the inflammation and inhibits the growth of bacteria. Some patients who are taking dapsone may suffer hypersensitivity reactions. DHS is characterized by a combination of fever, skin eruption, and internal organ involvement. In general, these symptoms will develop over the first six weeks of therapy. In this case, a 38-year-old female patient came to multispecialty hospital with complains of fever on and off since 13 days, skin lesions all over the body associated with itching since 7 days, swelling over face since 2 days. Symptoms and laboratory examination were found to be similar with Dapsone Hypersentivity Syndrome (DHS). This case report provides an understanding of DHS. Proper monitoring is necessary and timely laboratory findings should be obtained for less adverse events. Keyword: Dapsone, Dapsone Hypersensitivity Syndrome (DHS), Adverse Drug Reaction, Leprosy
Publication date: 01/03/2024

https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_7879.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.3.7879