ABSTRACT

High blood pressure, sometimes known as hypertension, is a frequent disorder marked by unusually high blood vessel pressure. Many people get hypertension (HT), especially as they age. Although it is not a disease in and of itself, it is a substantial risk factor for cardiovascular mortality and morbidity. A more recent combination on the market, Telmisartan and Bisoprolol Fumarate, is effective in treating hypertension. This combination was developed to improve Stage II hypertension therapy. A beta 1-selective compound known as bisoprolol fumarate is also known as bis(1-[(propan-2-yl) amino] Cardio selective adrenoceptor blocker: 3-(4-[2- (propan-2-yloxy) ethoxy] methylphenoxy) propan-2-ol. Chemically, telmisartan is a 2-4-[[4- methyl-6-(1-methylbenzimidazol-2yl)-2-propylbenzimidazol-1yl] methyl] biphenyl and an AT1-receptor blocker. It contains details on the development of several analytical techniques such UV, HPTLC, HPLC are methods reported for bisoprolol fumarate and telmisartan as single medications and in drug combinations. All procedures presented have been shown to be straightforward, precise, cost-effective, and repeatable. According to our knowledge, there have been two techniques described for the combination of bisoprolol fumarate SS and telmisartan, which is the topic of this review. Keywords: Bisoprolol fumarate, Telmisartan, Analytical Method, HPLC, HPTLC, UV
Publication date: 01/03/2024

https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_7848.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.3.7848