SALIVA AS A PROSPECTIVE DIAGNOSTIC MEDIUM FOR BACTERIAL BIOFILM PATHOGENICITY IN DIABETIC PATIENTS
Authors: Ramamurthy S , RAJA D, KRISHNAN H, RAMESH SN, SARAN SI, VIJAYAN NK AND SUKUMARAN BO*

ABSTRACT
Diabetic patients are at an increased risk of oral health problems, such as periodontal disease, caries, and candidiasis, due to their impaired immune response and changes in the composition of saliva. Studies have shown that saliva from diabetic patients has a different composition compared to saliva from healthy individuals, with its high levels of glucose, proteins and low level of antimicrobial peptides. These changes can create an environment that is more favourable for the growth of oral biofilm forming bacteria, such as Streptococcus mutans and Porphyromonas gingivalis. Analysis of saliva can provide important information about the presence of biomarkers for oral health problems, such as cytokines, enzymes, and growth factors. These biomarkers can be used to monitor the progression of oral infections and to evaluate the effectiveness of treatment. Saliva can be a useful tool in assessing oral health in diabetic patients, and has the potential to provide valuable information for the prevention and management of oral infections. Keywords:, Biofilm, Biomarkers, Diabetic, Infection, Saliva
Publication date: 01/03/2024
    https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_7843.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.3.7843