SALIVA AS A PROSPECTIVE DIAGNOSTIC MEDIUM FOR BACTERIAL BIOFILM PATHOGENICITY IN DIABETIC PATIENTS Authors: Ramamurthy S , RAJA D, KRISHNAN H, RAMESH SN, SARAN SI, VIJAYAN NK AND SUKUMARAN BO*
ABSTRACT
Diabetic patients are at an increased risk of oral health problems, such as periodontal disease,
caries, and candidiasis, due to their impaired immune response and changes in the composition
of saliva. Studies have shown that saliva from diabetic patients has a different composition
compared to saliva from healthy individuals, with its high levels of glucose, proteins and low
level of antimicrobial peptides. These changes can create an environment that is more
favourable for the growth of oral biofilm forming bacteria, such as Streptococcus mutans and
Porphyromonas gingivalis. Analysis of saliva can provide important information about the
presence of biomarkers for oral health problems, such as cytokines, enzymes, and growth
factors. These biomarkers can be used to monitor the progression of oral infections and to
evaluate the effectiveness of treatment. Saliva can be a useful tool in assessing oral health in
diabetic patients, and has the potential to provide valuable information for the prevention and
management of oral infections.
Keywords:, Biofilm, Biomarkers, Diabetic, Infection, Saliva Publication date: 01/03/2024 https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_7843.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.3.7843