ABSTRACT

Triclosan (TCS) is a broad-spectrum antimicrobial agent that is frequently used in pharmaceuticals and in consumer as well as personal care products like toothpaste, soaps, detergents, toys and surgical cleaning process. Reports have shown that TCS is a potential endocrine disruptor. TCS causes antimicrobial resistance and also causes disrupted hormonal development. This review covers analytical methods carried out on TCS from a time period of 1994 to 2014, which includes 26 analytical methods comprising Spectrophotometric and Chromatographic methods like RP- HPLC, UPLC, LC-MS-MS and GC-MS methods were reported. Currently, TCS in loaded in most of the products we consume and due to its potential estrogenic and androgenic activity, analytical chemistry had played an essential role in quantifying the content of TCS present in pharmaceuticals and consumer products. The application of these methods and determination of TCS in various sources are also been discussed. Keywords: Triclosan, Personal care products, Endocrine disruptor, Spectrophotometric and Chromatographic methods
Publication date: 01/03/2024

https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_7606.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.3.7606