PHARMACOEPIDEMIOLOGY, EFFICACY AND PRESCRIPTION PATTERN OF ANTIHYPERTENSIVE TREATMENT: CROSS SECTION OBSERVATIONAL STUDY Authors: Agalya V , AKSHAYA K, VINAYAGAMOORTHI N, PARIMALAKRISHNAN S* AND UMARANI R
ABSTRACT
Objective: Systemic arterial hypertension is usually asymptomatic, requires long term
treatment and the most important risk factors are cardiovascular mortality and morbidity. The
aim of this study is to assess the pharmacoepidemiology, efficacy and prescription pattern of
systemic hypertension.
Methods: A cross section observational study, conducted among 70 patients in a tertiary
teaching hospital located rural parts of India for 6 months. Standard questionnaires were used
to measure prevalence and prescription pattern for hypertension among the selected patients.
Results: Among 70 patients, 57.42% were female, majority of the patients were in the age
group between 60 and 69 (42.8%), 74.3% has good knowledge about HTN, 21.42% has
family history of HTN. 70.58% and 82.35% were smokers and alcoholic respectively. 68.1%,
60.3%, 46.1%, 42.2%, ACE Inhibitors, beta blockers, diuretics, and CCB respectively,
mostly prescribed. 51.4% were prescribed with 2 antihypertensive drugs. The mean systolic
and diastolic blood pressures were measured before and after treatment 160±6.71/96±2.79
and 145±4.82/92±3.01 mmHg respectively. 65.7% patients can able to attain the goals as per
the guidelines during this study.
Conclusion: Based on the above findings, it is to conclude that most of the patients had good
knowledge on hypertension. Combined antihypertensive treatment increases the chances for
achieving good control on blood pressure. Family history plays a major role in treating and
controlling the blood pressure. Good lifestyle practices like quitting smoking and drinking
also helps to control higher BP level. The prescription pattern shows that anti-hypertension
goals can easily attained with dual therapy.
Keywords: Pharmacoepidemiology, Hypertension, Anti-Hypertensive drugs,
Prescription pattern, Treatment pattern Publication date: 01/03/2024 https://ijbpas.com/pdf/2024/March/MS_IJBPAS_2024_6504.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.3.6504