ABSTRACT

Every plant on earth has been used for humans and other animals, according to ancient Indian literature. The primary bodily organ that controls homeostasis is the liver. It is engaged in practically all metabolic pathways that are connected to growth, the prevention of disease, the delivery of nutrients, the production of energy, and reproduction. Andrographis paniculata is a plant that is widely cultivated, and as more evidence emerges in favour of its several therapeutic benefits, its significance as a medicinal plant is increasing. With careful consideration of the plant's beneficial properties, it can be recommended as a secure, crucial medicinal herb for people. Numerous chemical components, primarily lactones, diterpenoids, diterpene glycosides, flavonoids, and flavonoid glycosides, are present in this herb. The main objective of this experiment was to find out the hepatoprotective activity of the formulation which is made up of Andrographis paniculata in albino wistar rats by investigating the various parameters like body growth and the liver function tests like Serum Glutamic Oxaloacetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT), and Alanine Transaminase (ALT) on Carbon tetrachloride (CCl4) induced experimental model. Keywords: Andrographis paniculata, Andrographolide, Silymarin, Carbon tetrachloride, Alcohol, Hepatoprotective
Publication date: 01/02/2024

https://ijbpas.com/pdf/2024/February/MS_IJBPAS_2024_7802.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.2.7802