ABSTRACT

In the present study, explains the detailed information about the synthesis of sliver nanoparticles using the flower and stem of Costus igneus which was used to determine the alpha amylase, alpha glucosidase inhibition assay and antioxidant activities are examined by DPPH (diphenyl-2 picrylhydrozyl) method. The characterization of synthesized silver nanoparticleswere confirmed by the UV-visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscope (SEM), Energy dispersive X-ray (EDX). The UV- visible spectroscopy was used to examine the silver nanoparticles and the peak range was observed at 436nm. The FTIR was used to analyses the functional group present in the plant extracts and silver nanoparticles. The SEM analysis showed the cubic and spherical shape of the synthesized silver nanoparticles. The elemental composition of the synthesized silver nanoparticles is determined by EDX analysis. The crystalline nature of the silver nanoparticles was analyzed by using XRD technique. The result shows that the flower-AgNPs exhibits inhibitory effect on alpha amylase (84.9%) and for the stem-AgNPs (82.5%). alpha glucosidase showed inhibitory effects in comparison with flower- AgNPs (58.3%) and stem-AgNPs (53.7%) by using standard acarbose drug. The antioxidant activities by DPPH method exposed activity for flower-AgNPs (81.3%) and for the stem- AgNPs (79.6%) were compared with standard ascorbic acid. The antiperiodontal analysis showed a better inhibition against streptococcus mutans, streptococcus salivaryus, streptococcus sobrinus and staphylococcus aureus. Therefore, it is suggested that the synthesized silver nanoparticles using flower and stem of Costus igneus extract as the good yield of inhibitor for diabetes and periodontitis. Keywords: Flower and stem-AgNPs of Costus igneus alpha amylase and alpha glucosidase inhibitory activity, antioxidant (DPPH) activity, antiperiodontal activity
Publication date: 01/02/2024

https://ijbpas.com/pdf/2024/February/MS_IJBPAS_2024_7787.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.2.7787