ABSTRACT

Liposomes are artificially prepared spherical-shaped vesicles made of lipid bilayers. Liposomes have greater advantages than current drug delivery systems, such as site-targeting, modified release, prevention from clearance and drug degradation, increased therapeutic effects, and less toxic side effects. Liposomes have wide clinical applications as diagnostic, anticancer, topical cosmetic products, pulmonary, food applications, and so on. In biological, pharmacological, nutritional, and medical research, liposomes are being studied extensively as drug carriers for enhancing the distribution of bioactive agents and many different compounds. Most of those with clinical approval have sizes between 50 and 300 nm. This article represents liposomes as drug delivery, their composition, and mechanism, methods of preparation, characterization, and evaluation. Some advanced technology in liposomal drug delivery routes is inhalation and ocular. Keywords: Liposomes, phospholipids, controlled delivery system, vesicles, encapsulation, active targeting
Publication date: 01/02/2024

https://ijbpas.com/pdf/2024/February/MS_IJBPAS_2024_7762.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.2.7762