ABSTRACT

Methanol was prepared from dried leaf parts of Basella alba by cold maceration method. Anxiolytic activity of the extract of B. alba was evaluated by diazepam induced by elevated plus maze on open and close arm and light and dark model by dark arm and light arm test in mice. Methanol extract (100 and 200 mg/kg, oral rout) showed highly significant (p<0.001) anxiolytic activity. All the results were compared with reference drug, diazepam. The presence of various phytoconstituents in the extracts was identified by preliminary phytochemical studies. The results of this study suggested that B. alba methanol extract possesses anxiolytic activity. Keywords: Basella alba, anxiolytic activity, elevated plus maze model, light and dark modeldiazepam, etc.
Publication date: 01/02/2024

https://ijbpas.com/pdf/2024/February/MS_IJBPAS_2024_7760.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.2.7760