ABSTRACT

Polymers are used to great extent in pharmaceutical industry for drug delivery because of their surface and bulk properties. They are also used in formulations of drug and devices for drug delivery. Polymeric Drug Delivery systems are used for controlled drug delivery ensuring patient compliance. Metallic Nanoparticles are proven to have antibacterial properties against both gram positive bacteria and gram negative bacteria. Some substances obtained naturally such as Honey, Aloevera, Tulsi, Turmeric, Garlic, Clove, Nutmeg, etc also contain antibacterial properties. This work demonstrates fabrication of polymeric composite of Gum guar (GG) and Starch (St). Then this polymeric composite was loaded with Aloevera and Lead (Pb) nanoparticles simultaneously. This polymeric composite was also characterized using several methodologies including X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FTIR), Scanning electron microscopy (SEM). Chemical properties were also determined using Swelling and Expansion experiments. Ultraviolet-Visible spectroscopy (UV-Vis) were also carried out for Lead Nanoparticles along with characterization of Aloevera by Ultraviolet-Visible spectroscopy (UV- Vis). Swelling test using pf solution was also carried out to evaluate swelling parameters. Also, expansion study was done using gelatin. Keywords: Gum Guar, Starch, Lead Nanoparticles, Aloevera, Gelatin
Publication date: 01/01/2024

https://ijbpas.com/pdf/2024/January/MS_IJBPAS_2024_7742.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.1.7742