ABSTRACT

CKD is the reduction in the GFR and urinary abnormalities or structural abnormalities of the renal tract. The aim of the study is to evaluate the prescribing trends of antihypertensives in chronic kidney disease patients. This is a retrospective observational study that was carried out in a tertiary care hospital for a period of 6 months in which data from January 2019 – January 2022 was collected from the Nephrology Department. A total of 178 cases of CKD were retrospectively analyzed, in which 107 were males and 71 were females. 129 patients had diabetes mellitus ,80 patients had coronary artery disease and 35 patients had dyslipidemia. 123 patients in this study had albuminuria and CCB was the most prescribed class of antihypertensive irrespective of all stages. There was a statistically significant difference between the prescription of antihypertensives among patients with albuminuria compared with patients without albuminuria and in the prescribing trends of diuretics, alpha blockers, ?- blockers and alpha agonists in various stages of CKD. The study was done to understand about the prescribing trends of antihypertensives in CKD patients. The study concluded that CCBs were the topmost prescribed class of antihypertensive drugs in all stages of CKD and CCB+AA was the frequently prescribed combination therapy for CKD. Keywords: Chronic kidney disease, albuminuria, GFR, prescription pattern
Publication date: 01/01/2024

https://ijbpas.com/pdf/2024/January/MS_IJBPAS_2024_7678.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.1.7678