ABSTRACT

Background: Oral cancer is a prevalent and serious health concern in the Indian subcontinent. This study aims to investigate the efficacy of povidone iodine (5%) compared to chlorhexidine mouthwash (0.2%) in managing oral mucositis and pain induced by radiotherapy. Aim: To compare & study the effectiveness of povidone iodine (5%) verses chlorhexidine mouth wash (0.2%) on oral mucositis and pain induced by Radiotherapy. Materials & Method: A Simple factorial design was conducted in Apollo Hospitals-Gandhinagar, to study and assess the effectiveness of povidone iodine (5%) verses chlorhexidine mouth wash (0.2%) of oral mucositis and pain induced by Radiotherapy. A simple random under simple lottery method were selected 180 head and neck cancer patients with oral mucositis and pain and was collected data after obtaining the consent from the patients or family members. The obtained data were analysed using SPSS-20 software, descriptive statistics were used to describe the samples characteristics, the degree of freedom were analysed. Moreover, Chi-square test used. The level of significance was set at p<0.005. Results: Povidone iodine demonstrated higher effectiveness in reducing mucositis and pain compared to chlorhexidine (p < 0.0001), indicating its superiority in managing these symptoms induced by radiotherapy. Conclusion: This studyaffirms the greater efficacy of povidone iodine over chlorhexidinegluconate in alleviating mucositis and associated pain. Keywords: Povidone iodine, Chlorhexidinegluconate, Mucositis, Pain, Cancer, Radiotherapy
Publication date: 15/12/2023

https://ijbpas.com/pdf/2023/December/MS_IJBPAS_2023_DECEMBER_SPCL_1082.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.12.1082