ABSTRACT

Due to the use of various formulation components, sprayable gel has so much beneficial advantages over other traditional topical drug delivery systems like cream, patches and ointment in terms of characterization, appearance, easy application, affability, conventional dosage design, reducing likelihood of skin irritation, and adhesive nature on the skin surface from the application site. However, there aren't as many transdermal sprayable gel products on the market as there are for other transdermal drug administration dosage forms. This review article focuses on the current state of sprayable gel formulation and evaluation in the context of its formation, with the effectiveness of choices of drug, penetration enhancers, volatile solvents, polymers and their evaluation parameters to be has to tested for the development of a more efficacious form of a dosage form like sprayable gel. Also discusses the types of polymers and excipients, sprayer types, its factors affecting on formulation and evaluations and analytic parameters for the determination of the ability to spray at the site of application and gel characteristics and with the natural and synthetic gelling agent and its characterization with the polymers and its future aspects via application of the dosage form. Keywords: Sprayable gel, Dosage form, Skin permeability, in-situ gelling
Publication date: 01/12/2023

https://ijbpas.com/pdf/2023/December/MS_IJBPAS_2023_7656.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.12.7656