ABSTRACT

Kidney stones or urolithiasis is a worldwide medical challenge to the urinary system. It is a multifactorial painful phenomenon that occurs due to various physiochemical alterations in the urinary tract like the imbalance between stone promoter and inhibitors, supersaturation, and many more. General causes of urolithiasis are insufficient urinary effluent, foreign matter in the urinary tract, bacterial infections, a diet rich in oxalates and calcium, vitamin A inadequacy, surplus of vitamin D and various metabolic ailments like hyperthyroidism, cystinuria, intestinal dysfunction and others. The recurrence rate of urolithiasis is also very high. Medicinal plants are always useful in the management of a variety of metabolic ailments because of the presence of their potential phytoconstituents. Several plants and phytoconstituents have been reported for their action against urolithiasis, So the current review article explains the role of promising potential active phytoconstituents in the treatment of urolithiasis as well as have a brief idea about medicinal plants that have important phytoconstituents but still have not been assessed for their anti-urolithiatic action. The current review covers the pathophysiology of stone formation along with the various approaches through which a kidney stone can be targeted. Keywords: Urolithiasis, Kidney stone, Berberine, Chemical constituents, Triterpenoids
Publication date: 01/12/2023

https://ijbpas.com/pdf/2023/December/MS_IJBPAS_2023_7601.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.12.7601