A RETROSPECTIVE STUDY ON THE ANTIPLATELET TREATMENT IN PATIENTS HAVING ACUTE CORONARY SYNDROME IN A TERTIARY CARE HOSPITAL Authors: Chacko BK , LIYA B , THOMAS N, JAMES R, SHAJAN R, JOSEPH JG AND MATHEWS SM
ABSTRACT
A retrospective study was conducted in Department of Cardiology at Pushpagiri Medical College
Hospital for a period of 6 months. The aim of the study was to study the prescribing pattern of
antiplatelet drugs in patients with acute coronary syndrome and to identify the risk factor associated
with acute coronary syndrome in a tertiary care hospital. In this study a total of 195 patients were
analyzed in which 62.2% were male and 31.79% were females and most of the patients were in the
age group 60-69years (34.87%). In our study population NSTEMI was found to be more prevalent
than STEMI and unstable angina. Most common risk factor associated with ACS were hypertension
(52.82%) and the most commonly prescribed antiplatelet therapy was dual therapy with aspirin and
clopidogrel. The study conclude that dual therapy is more effective than monotherapy which is
statistically significant (P value<0.001). The study revealed that the most commonly prescribed
antiplatelet therapy was aspirin and clopidogrel. Pharmacist are in an ideal position to review the
patient`s risk factors for ACS and to initiate or recommend appropriate pharmacotherapy where
indicated. Therefore, the integration of role of the pharmacist in the management of ACS is very
crucial and improves the outcome of the patient.
Keywords: Acute coronary syndrome, antiplatelet therapy, risk factors, hypertension,
monotherapy, aspirin, clopidogrel Publication date: 01/11/2023 https://ijbpas.com/pdf/2023/November/MS_IJBPAS_2023_7549.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.11.7549