ABSTRACT

The present study aimed with the potential anthelmintic activity against Tubifex tubifex followed by Taenia solium with the ethanol leaves extract of Macaranga indica (Family: Euphorbiaceae) leaves at varied concentrations of 12.5, 25, 50 and 75 mg/ml. The study was compared with standard albendazole (50 mg/ml) as control. Initially, ethanol extract of plant leaves was subjected to phytochemical screening for the presence of various bioactive components followed by HPLC analysis for the presence of flavonoid compounds, quercetin. Anthelmintic activity study was carried out in terms of paralysis and death time on the above said test worms. The activity was compared with standard albendazole. Finally, the result revealed that dose dependent activity of the extract and the activity were may be due to the presence of quercetin in the extract. Keywords: Albendazole, anthelmintic activity, Macaranga indica, Taenia solium, Tubifex tubifex
Publication date: 01/11/2023

https://ijbpas.com/pdf/2023/November/MS_IJBPAS_2023_7495.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.11.7495