ABSTRACT

Diabetes mellitus, a chronic metabolic disorder, is affecting a significant portion of the global population. Traditional medicines have shown potential in managing diabetes with reduced side effects and holistic health benefits. The present study aimed to develop a polyherbal tablet formulation comprising extracts of Azadirachta indica, Allium sativum, and Annona squamosa and assess its antidiabetic efficacy in alloxan-induced diabetic rats. The extracts' phytochemical profile was characterized, followed by the formulation of tablets using appropriate excipients. The tablets' efficacy was evaluated based on various biochemical parameters, including serum glucose and glycated hemoglobin levels. Results demonstrated that the polyherbal formulation exhibited significant antidiabetic effects, potentially attributed to the synergistic action of bioactive compounds present in the herbal extracts. The study highlights the potential of integrating traditional herbal medicine into modern therapeutic strategies for diabetes management. Keywords: Diabetes mellitus, Polyherbal tablets, Azadirachta indica, Allium sativum, Annona squamosa, Alloxan-induced diabetes, Phytochemical profile, Antidiabetic efficacy
Publication date: 15/10/2023

https://ijbpas.com/pdf/2023/October/MS_IJBPAS_2023_OCTOBER_SPCL_1051.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.10.1051