ABSTRACT

Staphylococcus aureus is becoming a more vulnerable pathogen common in the community and hospitals, resulting in more cases of illness and deaths. Irrational antibiotic use has been linked to Staphylococcus aureus infection, which has worsened the already concerning situation and led to endemic and epidemic diseases worldwide. The need to develop traditional herbal medicine into a sophisticated Ayurvedic Medicinal System (AMS) strategy is driven by the current threat of antibiotics and their resistance to public health. The current study uses herbal informatics as a comprehensive approach in identifying the effective herbal remedies to counter the threat posed by Staphylococcus aureus. Six plants were optimized and may be further validated at the preclinical level after being tested against the virulence factors of the bacterium using a systematic bioprospecting approach. The leads/drug-like herbals identified by the herbal informatics model could be helpful for in vitro and in vivo research to create therapeutic herbal medicines. Keywords: Bioprospection; Staphylococcus aureus; Traditional medicine; Ethnopharmacology
Publication date: 15/10/2023

https://ijbpas.com/pdf/2023/October/MS_IJBPAS_2023_OCTOBER_SPCL_1043.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.10.1043