Background: For drug discovery and development of novel therapeutic agents against
diseases, understanding phytochemistry in plants is very crucial. Objective: The aim of this
research was to identify the phytochemical profile of ethanolic extract of Convolvulus
pluricaulis (CP), Michelia champaca (MC), and Chromolaena odorata (CO) by using LC-MS
technique. Materials and Methods: The extract of selected plants by soxhlet extraction
technique was prepared by using ethanol as a solvent. The extract was subjected to LC-MS
analysis and the identified constituents were further reviewed for their pharmacological
potentials. Results: LC-MS findings has provided significant contribution in identification of
phytoconstituents in herbs belonging to a) phenolic compounds - flavonoids,
phenylpropanoids; b) alkaloids - amide, proline and quinoline and c) pentacyclic triterpenes.
Phenolic compounds - Rutin, Quercetin-3-?-D-glucoside, Genistein, Biochanin A, Puerarin,Orientin, Luteolin, Cynaroside, Tangeretin, Nobiletin, Sakuranetin, Hesperetin, 7-
hydroxycoumarin, 6-Gingerol and 2-Methoxyresorcinol were identified in plants. Alkaloids –
Piperine, DL-Stachydrine and 8-hydroxyquinoline were identified. Pentacyclic triterpenes
betulin was identified. Conclusion: In this research study, different phytoconstituents of
pharmacological significance was identified in all the three plants by LC-MS technique. Hence,
these plants are indicative of potential for medicinal use and the further researchers could work
with these plants individually or by combination (polyherbal formulation) using related in-vitro
and in-vivo models.
Keywords: Phytoconstituents, LC-MS, Convolvulus pluricaulis, Michelia champaca,
Chromolaena odorata, Pharmacology
Publication date: 15/10/2023
https://ijbpas.com/pdf/2023/October/MS_IJBPAS_2023_OCTOBER_SPCL_1023.pdf
Download PDF
https://doi.org/10.31032/IJBPAS/2023/12.10.1023
