ABSTRACT

Obesity significantly affects the fertility and sperm quality in men at reproductive ages through hormonal imbalances, increased scrotal temperatures, thus decreasing the concentration and motility of sperm, decreased total sperm count, increased DNA fragmentation index, decreased sperm movement and sperm quality. Obese men suffer from hormonal imbalances, increased oestrogen levels, and low levels of inhibin-B and androgen, which affect sperm production. The present review discusses how obesity affects male fertility and sperm quality, as well as various treatment options. The men infertility due to obesity can be treated by changing in lifestyle, increasing physical activity, and behavioral treatment; Pharmacological intervention such as medication and food supplements involving weight loss medicines, appetite suppressants, and aromatase inhibitors; Surgical treatment including scrotal lipectomy and bariatric surgery, Assisted reproductive technology (ART) including In vitro fertilization (IVF), Intrauterine insemination (IUI), and Intracytoplasmic sperm injection (ICSI). Keywords: Obesity, Men infertility, body mass index, Management, Assisted Reproductive Technology
Publication date: 01/09/2023

https://ijbpas.com/pdf/2023/September/MS_IJBPAS_2023_7434.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.9.7434