DETERMINATION OF BISOPROLOL FUMARATE AND ITS METABOLITES IN BIOLOGICAL, PHARMACEUTICAL AND ENVIRONMENTAL SAMPLES BY DIFFERENT ANALYTICAL TECHNIQUES
Authors: Alam F , JUDDER MI*, ISLAM M, RAHMAN R, PATHAK B AND RAHMAN Z

ABSTRACT
Purpose: Bisoprolol fumarate is considered to be one of the most crucial beta-blockers that are needed for biological preparation and pharmaceutical fluids. Now in recent times, there are multiple analytic techniques developed for the determination of bisoprolol activity. Data collection: The collection of data has been done by information searching from Google scholar and Proust consisting of peer-reviewed articles. Pharmaceutical preparation, bisoprolol are the important keywords that have searched for the proper technique of analyzing the study. Results: Results of the study is observed to be maintained by some methods which are favourable for the quantification in this scenario. Moreover, it focused on spectrophotometric, HPLC and some other methods that are beneficial for determining BSL quantification. In the case of the quantification of the raw materials, the HPLC method is considered to be one of the best analytical techniques because it has a high range of productivity. Conclusion: Quantification and the technique of limit detection is the first and foremost crucial technique that can be applied under the HPLC method for the best outcome. Regulation and limitation of pH are also important in this scenario because they generate a high range of productivity. Keywords: Bisoprolol, spectrophotometry, HPLC, analytical techniques, BSL quantification, limit detection
Publication date: 01/09/2023
    https://ijbpas.com/pdf/2023/September/MS_IJBPAS_2023_7433.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.9.7433