ABSTRACT

Dendrimers are modern nano-polymeric globular architectures that are three-dimensional, hyperbranched. They differ from other polymers due to important characteristics such their nanoscopic size, narrow polydispersity index, effective molecular structure regulation, peripheral availability of different functional groups, and internal cavities. Also, in this study we have discussed about the various ways of modification of the Nanoparticles and Dendrimers such as: PEGylated dendrimers as a brain-targeting tool, Medication delivery to the mind by PEGylated dendrimers, etc., as well as other modifications. PEGylation is a technique for optimizing targeted brain delivery. We have also discussed the role of Nano-technology in enhancing physicochemical properties of ETS (Etoposide), Progressed Nano carriers tend to improve solvency/disintegration of the fat-soluble drugs. And in the last section we have discussed about the various kinds of Dendrimers like: Polyether dendrimers, Polypropylene imine (PPI) dendrimers, etc., and the applications of dendrimers in various fields. Keywords: Dendrimers, PEGylation, Modification, Hyper-branched, Nanoparticles, Target Delivery, Polyether dendrimers, Polypropylene imine (PPI)
Publication date: 01/09/2023

https://ijbpas.com/pdf/2023/September/MS_IJBPAS_2023_7419.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.9.7419