ABSTRACT

As precursor cells with the ability to self-renew the stem cells are used widely in treatment of diseases. Clinical research on stem cell-based treatments has improved significantly during the past few years. The process of stem cell specialization is influenced by both internal signals, which are governed by genes in DNA, and external cues, such as physical contact between cells or chemical secretion by surrounding tissue. Because of their pluripotency property the stem cell can develop into any cell type. In the bone marrow, these cells mostly transform into fat, bone, and cartilage cells. Pluripotent cells are referred to be totipotent if they have the ability to develop extraembryonic tissues in embryos. The stem cell can be classified into according to their differentiation and origin. According to their differentiation they can be classified into totipotent, pluripotent, multipotent, unipotent, oligo potent. According to their origin stem cell can be classified into embryonic stem cell, embryonic germ stem cell, Umbilical cord cell etc. They stem cell has wide range of application in the diseases like Heart failure, Diabetes mellitus, Parkinson disease liver disease etc. Keywords: Clinical research, Totipotent, Pluripotent, Umbilical cord cells
Publication date: 01/09/2023

https://ijbpas.com/pdf/2023/September/MS_IJBPAS_2023_7412.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2023/12.9.7412