Nigella sativa is a commonly used medicinal plant all over the world. Nigella sativa seed, sometimes
known as black seed, has been used as a natural cure for a variety of diseases in various cultures for
ages. Thymoquinone, thymohydroquinone, dithymoquinone, thymol, carvacrol, nigellimine,
nigellicine, nigellidine, and alphahederin are among the active ingredients. It was discovered to have a
variety of pharmacological effects on various body organs. It is being used as antihypertensive, liver
tonics, diuretics, digestive, anti-diarrheal, appetite stimulant, analgesics, anti-bacterial, and in skin
problems, it has been widely utilized. Various researchers have conducted extensive research on
N.Sativa , and a wide range of its pharmacological actions have been investigated, including
antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, spasmolytic,
bronchodilator, hepato-protective, renal protective, gastro-protective, antioxidant properties, and so
on. The medical effects of Nigella sativa have been noted in ancient systems such as Unani, Chinese
traditional medicine, and Ayurveda. It also has antiviral, antioxidant, anti-inflammatory,
anticoagulant, immunomodulatory, bronchodilatory, antihistaminic, antitussive, antipyretic, and
analgesic properties, according to recent pharmacological investigations. The active compounds of
N.Sativa , such as nigellidine and -hederin, have been identified as potential SARS CoV-2 inhibitors;
this activity might be tested clinically in COVID-19 patients.
Keywords- Immunomodulator, Kalonji, Nigella sativa, Unani
Publication date: 01/09/2023
https://ijbpas.com/pdf/2023/September/MS_IJBPAS_2023_7333.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.9.7333
