ABSTRACT

The aim of present study was to investigate the phytochemical analysis and immunomodulatory activities of ethanolic extract of nuts of Anacardium occidentale Linn in experimental animal of three different dose viz.150, 300 and 450 mg/kg. Nut extracts of Anacardium occidentale Linn revealed that presence of several biologically active component that include flavonoids, alkaloids, glycosides, phenols, tannins, vit C and quercetin. The immunomodulatory activities were determined by phagocytic activity, delayed type hypersensitivity (DTH), neutrophil adhesion test, haemagglutination antibody (HA) titer response and T cell population Assay. The response produced by oral administration of ethanolic nut extracts of Anacardium occidentale Linn showed a significant dose dependent increase in Phagocytic activity, DTH response, neutrophil adhesion response, augmentation of humoral immune response to sheep red blood cells and increase in T cell population response. This study demonstrates immunomodulatory activities and therapeutic potential of phytochemical components extracted from Anacardium occidentale Linn to combat against immunological disorders. Keywords: Anacardium occidentale Linn, immunomodulatory activity, phytochemical analysis
Publication date: 01/08/2023

https://ijbpas.com/pdf/2023/August/MS_IJBPAS_2023_7354.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.8.7354