Thespesia populnea, commonly known as Paras Peepal is a large tree belongs to the family
Malvaceae. It is found in tropical and coastal regions of India. The various parts of the tree are
traditionally used for anti-inflammatory, hepatoprotective, anti-psoriasis, anti-diabetic, wound
healing properties. The present study was done to identify the phytocompounds in methanolic
extract of Thespesia populnea leaf (METPL) &and fruits (METPF) through Thin Layer
Chromtography (TLC) & Gas Chromatography – Mass Spectrometry (GC-MS) techniques. The
preliminary phytochemical screening showed the presence of various phytochemicals like
Glycosides, Phenol, Tannins, Flavonoids, Phytosterols, Saponins, Steroid, Phenols, and
Quininesetc. In a GC-MS examination of the said extracts, over200 compounds were attributed
through Mass spectra matching with the National Institute Standard and Technology (NIST)
database (ver. 2011). Out of them, 23 compounds like3-Eicosyne, 9-Octadecen-1-ol, (Z)-, n-
Hexadecanoic acid, Octadecanoic acid, Octadecanoic acid 2-(2-hydroxyethoxy)ethyl
ester,Dodecanoic acid, Heptadecane, 2,6,10,15-tetramethyl-, 2-methyloctacosane,n-
Hexadecanoic acid, Octadecanoic acid, Undecanoic acid, Palmitoleic acid, Oleic Acid, 6-Octadecanoic acid etc. were identified in 39.83% peakarea of the chromatogram. Further, on
cross matching of the identified compounds at international compounds databases like
PUBCHEM, the tree is found having compounds relating to antimicrobial, anti-inflammatory,
antioxidant, anti-tumor, anti-inflammatory, antibacterial, antifungal, anti-viral medicinal
properties. Therefore, Thespesia populnea can be a good source of pharmacological agents
against infectious and life style disorders. Further studies may prove it a plant of great source of
therapeutic agents.
Keywords: Paras peepal, Thespesia populnea, Indian Tulip, Thin Layer Chromatography,
GC-MS analysis, PubChem, Phytochemical compound screening
Publication date: 01/08/2023
https://ijbpas.com/pdf/2023/August/MS_IJBPAS_2023_7326.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.8.7326
