HEMATOLOGICAL PROFILE OF PATIENT WITH SICKLE CELL ANEMIA AND IRON DEFICIENCY ANEMIA FROM RURAL VADODARA DISTRICT: A HOSPITAL BASED RETROSPECTIVE STUDY
Authors: Mitisha C , APURVAKUMAR P, HEMANTKUMAR P AND ANKITA P*

ABSTRACT
Background: Sickle Cell Anemia (SCA) and Iron Deficiency Anemia (IDA) are most prevalent public health problems in rural belt of Vadodara district. Sickle cell anemia is a genetic disorder which is identified by severe hemolytic anemia. Iron deficiency anemia is the primary common nutritional shortage in the world, because of when dietary iron absorption is insufficient to meet physiological requirements. Objective: To compare hematological characteristics of patient with sickle cell anemia and iron deficiency anemia. Method: A retrospective study was carried out at Parul Sevashram Hospital (PSH), Vadodara. Data were collected from 1st August 2021 to 31st January 2022. Records of all patients with sickle cell anemia and iron deficiency anemia were reviewed for the study. Data from records were extracted in excel sheet. Data were analyzed using descriptive statistics. Result: Study population constituted total number of 158 cases of anemia (55 sickle cell anemia and 103 iron deficiency anemia). Hematological profile of patients aging from 2 to 80 years of age (SCA: 2 to 45 years of age; IDA: 3 to 80 years of age) is presented. Differences in hematological profile of both SCA and IDA was noted. In terms of age, there wide difference noted (mean age: 21.32 SCA & mean age: 42.77 IDA). In SCA, Hb (8.63 ± 2.29), MCHC (31.38 ± 1.82) and RDW (20.67 ± 6.90) were dominant characteristics while in iron deficiency anemia RBC (6.79 ± 29.48), HCT (27.41 ± 4.57), MCV (83.42 ± 10.89), and MCH (25.95 ± 3.73). Very few patients (7%) were reported with SCA after age of 35, however, IDA was present in many patients (68.9%) above age of 35. Conclusion: Major differences were noted in the hematological profile of SCA and IDA. Keywords: Sickle cell anemia, iron deficiency anemia, hematological profile, rural hospital, western India
Publication date: 01/05/2023
    https://ijbpas.com/pdf/2023/May/MS_IJBPAS_2023_70971.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.5.7097