A REVIEW ON ANALYTICAL METHOD DEVELOPMENT OF ANTIHYPERTENSIVE AGENTs Authors: Ganwani A , PATEL Z*, BHAVSAR P AND PATEL L
ABSTRACT
Metoprolol Succinate {butanedioic acid; 1-[4-(2-methoxyethyl) phenoxy]-3-(propan 2-yl amino)
propan-2- ol} and Isosorbide mononitrate (8-nitrooxy-2,6-sdioxabicyclo[3.3.0]octan-4-ol) are
well known antihypertensive and antianginal agent. In this review article we discuss about
various analytical methods like Uv Spectroscopy, HPLC, HPTLC, Stability indicating RP-
HPLC, LC-MS, GC-MS for the estimation Metoprolol succinate and Isosorbide mononitrate
alone or in combination with other drugs. Analytical method development is the important part
Quality assurance and Quality control for IPQC testing of various drug substances and drug
product. So this study will helpful for researcher for the development of analytical method for
estimation of New Drug substances. Publication date: 01/07/2023 https://ijbpas.com/pdf/2023/July/MS_IJBPAS_2023_7311.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.7.7311