A REVIEW ON ANALYTICAL METHOD DEVELOPMENT OF ANTIHYPERTENSIVE AGENTs
Authors: Ganwani A , PATEL Z*, BHAVSAR P AND PATEL L

ABSTRACT
Metoprolol Succinate {butanedioic acid; 1-[4-(2-methoxyethyl) phenoxy]-3-(propan 2-yl amino) propan-2- ol} and Isosorbide mononitrate (8-nitrooxy-2,6-sdioxabicyclo[3.3.0]octan-4-ol) are well known antihypertensive and antianginal agent. In this review article we discuss about various analytical methods like Uv Spectroscopy, HPLC, HPTLC, Stability indicating RP- HPLC, LC-MS, GC-MS for the estimation Metoprolol succinate and Isosorbide mononitrate alone or in combination with other drugs. Analytical method development is the important part Quality assurance and Quality control for IPQC testing of various drug substances and drug product. So this study will helpful for researcher for the development of analytical method for estimation of New Drug substances.
Publication date: 01/07/2023
    https://ijbpas.com/pdf/2023/July/MS_IJBPAS_2023_7311.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.7.7311