ABSTRACT

Heterocyclic compounds portray as a major part in medicinal chemistry. Distinct derivatives of heterocyclic compounds are effectives for the numerous medicinal activity. S-triazine is the earliest known heterocyclic compounds. They are available in cheap price and have distinct biological activity. Because of this researchers get attracted toward this heterocyclic compound for the synthesis of newly derivatives. They are weak base and utilize to make a potent drug, & have a different pharmacological actions. Triazine compounds are six membered hetrocyclic compound bearing triple nitrogen atoms. Based on the position of a nitrogen atoms there are 3 different triazines compound called as 1,2,3 triazine, 1,2,4 triazine, & s- triazine respectively. Triazines are the significant core structure with bioactive characteristics. Number of triazines derivative are synthesize and assess for it abundant biological activities. Several derivative of triazine are better and have higher pharmacological action when compared to the standard drugs. The triazine reveals broad biological actions comprising antimicrobial, PI3K inhibitors, Antileshmanial, Anticancer, Anti HIV, Anti Plasmodial, Anti TB. Thus the triazines are believed to be the lead molecule for drug design and for drug discovery. Keywords: Lead molecule, Triazine, PI3K inhibitors, Anticancer, Antileshmanial, Drug desig
Publication date: 01/07/2023

https://ijbpas.com/pdf/2023/July/MS_IJBPAS_2023_7250.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.7.7250