ABSTRACT

Marsilea quadrifolia is a well-known medicinal plant, traditionally used in various ailments. In this study, we aimed to evaluate the anthelmintic activity of the hydro-alcoholic extract of Marsilea quadrifolia leaves. The hydro-alcoholic extract of Marsilea quadrifolia leaves was prepared using cold percolation methods, and the phytochemical analysis was performed. The anthelmintic activity of the extract was evaluated using the Limit test, Main test, and comparative study. The results showed that the hydro-alcoholic extract of Marsilea quadrifolia leaves exhibited significant anthelmintic activity. The time taken for paralysis and death of the Tubifex tubifex was noted to find out the minimum concentration of dose that was responsible for the death of all animals within 5 hours and the potency of the test substance as compared to the control standard Albendazole, and herbal standard. The phytochemical analysis of the extract revealed the presence of various bioactive compounds such as alkaloids, flavonoids, tannins, and saponins, which might be responsible for the observed anthelmintic activity. Therefore, the hydro-alcoholic extract of Marsilea quadrifolia leaves can be considered as a potential natural anthelmintic agent. Keywords: Marsilea quadrifolia, hydro-alcoholic extract, phytochemicals, anthelmintic activity
Publication date: 15/06/2023

https://ijbpas.com/pdf/2023/June/MS_IJBPAS_2023_JUNE_SPCL_1063.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.6.1063