ABSTRACT

Objective Intraoperative squash smear cytology (ISSC) is a simple, rapid, inexpensive and fairly accurate tool to diagnose CNS neoplasms intraoperatively. It can help the surgeon to modify the approach intraoperatively based on preliminary impression of lesion on cytology. Aim of this study is to find out the accuracy and utility of ISSC technique as a standalone method for rapid diagnosis of CNS lesions. Materials And Methods A total of 94 cases of CNS lesions were examined by squash smear technique for cytological diagnosis which were then compared with histopathological diagnosis provided on paraffin embedded sections which was taken as gold standard. Results An accuracy of 80.4% was achieved by Squash smear cytology. Of the total 94 cases, 82 were concordant with the final histopathological diagnosis, while 12 were discordant. The discrepancies were due to interpretational errors in 8% of the cases and sampling errors in 4% of the cases. Conclusion Squash smear cytology proved to be a simple, rapid, inexpensive and fairly accurate tool for intraoperative diagnosis of CNS lesions. Thorough sampling, clinicoradiological correlation and awareness about possible diagnostic pitfalls while reporting helps in achieving better diagnostic accuracy. Keywords: CNS lesions, Discordant, Intraoperative squash smear cytology, Meningioma
Publication date: 01/06/2023

https://ijbpas.com/pdf/2023/June/MS_IJBPAS_2023_JUNE_SPCL_1015.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.6.1015