Helminthiasis, a parasitic worm infection, is caused by Helminthic parasites like flatworms,
pinworms, roundworms, hookworms, tapeworms, etc. There are many potential drugs available
for the treatment of Helminthiasis. Albendazole and a few other benzimidazole derivatives are
one of them. Albendazole has adverse effects like stomach pain, nausea, vomiting, headache,
dizziness, and reversible hair loss. Further, consumption of such drugs in children may lead to
severe adverse effects such as fever, chills, sore throat, mouth sores, light-headed feeling,
seizure, ringing in the ears, vision problems, increased pressure inside the skull, and pain behind
the eyes. This drug is contraindicated in pancytopenia, low blood count due to bone marrow
failure, anemia, liver problems, low WBC count, and pregnancy. Therefore, a substantial unmet
need is required to develop some advanced anthelmintic agents with minimal adverse effects.
Keywords: Fascioliasis, Trypanosomiasis, Onchocerciasis, Neurocysticercosis, Theileriosis,
Endoectocide
Publication date: 01/06/2023
https://ijbpas.com/pdf/2023/June/MS_IJBPAS_2023_7212.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.6.7212
