SCREENING ANIMAL MODELS OF HEPATOPROTECTIVE AGENTS – A REVIEW Authors: Janve Y* And Kakadiya J
ABSTRACT
The liver is the body's largest and most essential organ, responsible for food and medication
metabolism. Humans are susceptible to liver disorders, which can be fatal. Excessive alcohol
use, toxic chemicals (some chemotherapeutic medicines, anti-biotics, carbon tetrachloride
(CCl4), paracetamol (PCM), thioacetamide (TAA), and microorganisms, among others) have all
been linked to liver cell harm. The current review focuses on the liver, its function, hepatic
illnesses, drug-induced hepatotoxicity, and the mechanisms that cause liver damage, as well as
the clinical situation.
Keywords: Liver, Hepatotoxicity, Paracetamol, Liver Damage, Carbon tetrachloride Publication date: 01/06/2023 https://ijbpas.com/pdf/2023/June/MS_IJBPAS_2023_7186.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.6.7186