ABSTRACT

Salbutamol is a potent anti-asthmatic agent, is a short-acting ?2-adrenergic receptor agonist act, Salbutamol and terbutaline are similar ?-2 adrenoceptor agonists that are believed to exert their maximal therapeutic effect through bronchodilation. Stimulation of ?-2 receptors in airway smooth muscle induces the cyclic AMP (c-AMP) pathway. In the present study, an attempt has been made to study various analytical methods for determination of salbutamol from different dosage form, these methods can be successfully applied for determination of salbutamol. The HPLC, UV, AAS, HPTLC, capillary electroscopic methods are available for assessment of salbutamol. Keywords: ?2-agonist HPLC, HPTLC, COPD, analysis
Publication date: 01/05/2023

https://ijbpas.com/pdf/2023/May/MS_IJBPAS_2023_7158.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.5.7158