ALGINATE AS POTENTIAL MUCOSAL DRUG DELIVERY SYSTEM Authors: Karmakar S , MANNA S, DAS S AND BHOWMIK M*
ABSTRACT
Alginate is a naturally occurring polysaccharide from marine-sourced brown algae. Its
physicochemical properties like solubility, biodegradation, and biocompatibility make it
useful in drug delivery. The mucoadhesive property of alginate indicates its use as a potential
drug carrier in mucosal delivery systems. In the recent past, delivery of drugs on the mucosal
side has been dramatically increased due to prolonged residential time, localised drug action,
lower systemic drug concentration, and bypassing of the first pass metabolism. This review
article provides an overview of alginate and its use as different drug carriers in mucosal
delivery systems.
Keywords: Alginate, Mucoadhesive, Mucosal delivery system, Drug carrier Publication date: 01/05/2023 https://ijbpas.com/pdf/2023/May/MS_IJBPAS_2023_7129.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.5.7129