ABSTRACT

This study principally focuses on method development and validation of UV spectroscopy for assay of Molnupiravir in pure and pharmaceutical dosage forms. This method includes preparation of standard and working solutions of a Molnupiravir Drug and later aliquots of working solution of different concentrations were prepared and analysed. Then this established method had been validated for linearity, precision, accuracy, robustness, and ruggedness, limit of quantification and limit of detection. From the data obtained, it is clear that the method developed is sensitive and accurate within range of 2-12?g/ml. The correlation coefficient (R2) was found to be 0.999. There is no interference observed with excipients in capsule formulation. The project method may be duly applied for the analysis of Molnupiravir in bulk for routine analysis. Keywords: Ultraviolet Spectroscopy, validation, Molnupiravir, method development, assay
Publication date: 01/05/2023

https://ijbpas.com/pdf/2023/May/MS_IJBPAS_2023_7096.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.5.7096